# GLP-1 Weight-Loss Results: What the Trials Actually Show > What to realistically expect from GLP-1 medicines: the trial numbers for Mounjaro, Wegovy, the Wegovy pill and Foundayo, minus the hype. Source: https://comparepharmacyscore.com/html/glp-1-glp-1-weight-loss-results.html Publisher: Pharmacy Score (comparepharmacyscore.com), free and independent Author: John Longton, GPhC Mock Inspection Service Auditor Last reviewed: 24 September 2026 --- - [Home](https://comparepharmacyscore.com/) - [Guides](https://comparepharmacyscore.com/html/guides.html) - GLP-1 weight loss results [GLP-1](https://comparepharmacyscore.com/html/glp-1-glp-1-prices.html) · Pharmacy Score # GLP-1 weight loss results. What to realistically expect from GLP-1 medicines: the trial numbers for Mounjaro, Wegovy, the Wegovy pill and Foundayo, minus the hype. In short What to realistically expect from GLP-1 medicines: the trial numbers for Mounjaro, Wegovy, the Wegovy pill and Foundayo, minus the hype. Pharmacy Score is free and independent: every pharmacy it lists is GPhC register-verified, every score is the provider’s real Trustpilot rating, and live GLP-1 prices are one click away via the trackers below. Marketing loves a big number. Here's what the clinical trials actually measured, average body-weight loss at the highest dose, over roughly 72 weeks, alongside diet and activity changes: - **Mounjaro (tirzepatide)**: around 20 to 22.5% average at the highest doses, the class leader - **Wegovy injection (semaglutide 2.4mg)**: around 15%; up to roughly 20% at the 7.2mg dose - **Wegovy pill (oral semaglutide)**: around 13.6 to 14% - **Foundayo (orforglipron)**: 11.2% at the highest dose in ATTAIN-1 ### Reading those numbers honestly They're averages, individual results spread widely in both directions. They assume consistent use over more than a year. And weight typically returns if the medicine stops without other changes in place, which is why Foundayo's licence covering weight maintenance after injections matters. Higher efficacy usually means a higher price, but the right medicine is the one a prescriber matches to your health, then you find its best price: [Monj](https://monj.co.uk) · [iGovy](https://igovy.co.uk) · [oGovy](https://ogovy.co.uk) · [Dayo](https://dayo.co.uk). ## Live prices, per medication. [Mounjarotirzepatide · once-weekly injectionMonj.co.uk →](https://comparepharmacyscore.com/html/mounjaro-prices.html)[Wegovysemaglutide · once-weekly injectioniGovy.co.uk →](https://comparepharmacyscore.com/html/wegovy-prices.html)[Wegovy Pilloral semaglutide · once-daily tabletoGovy.co.uk →](https://comparepharmacyscore.com/html/wegovy-pill-prices.html)[Foundayoorforglipron · once-daily tabletDayo.co.uk →](https://comparepharmacyscore.com/html/foundayo-prices.html) ## The official sources, in one place. These are the bodies that actually regulate, appraise and advise. If anything you read anywhere (including here) disagrees with them, believe them. [GPhC registerCheck any pharmacy's registration before you order, free and instant.](https://www.pharmacyregulation.org/registers/pharmacy)[MHRA: buying medicines onlineThe regulator's official advice on buying medication safely on the internet.](https://www.gov.uk/guidance/buy-medicines-online)[MHRA Yellow CardReport a side effect from any medicine, it takes five minutes and it matters.](https://yellowcard.mhra.gov.uk/)[NICE: semaglutide (TA875)The evidence-based NHS guidance for Wegovy in weight management.](https://www.nice.org.uk/guidance/ta875)[NICE: tirzepatide (TA1026)The evidence-based NHS guidance for Mounjaro in weight management.](https://www.nice.org.uk/guidance/ta1026)[NHS: obesityNHS overview of treatment options, including when medicines are considered.](https://www.nhs.uk/conditions/obesity/)[NHS: Better HealthFree NHS support for losing weight, with or without medication.](https://www.nhs.uk/better-health/lose-weight/)[electronic medicines compendiumThe official patient information leaflets for every licensed UK medicine.](https://www.medicines.org.uk/emc)